Correlation between children’ s adaptation to kindergarten and their temperament type / 上海预防医学

[Objective] To explore the relationship between children ’ s adaptation to kindergarten and their temperament type . [ Methods ] Initial survey: A self-made questionnaire was used to collect the relevant information.After that,a behavior screening questionnaire (BSQ) for 3 to 7 year old children was applied to assess the temperament type of those who were new to the kindergarten .Longitudinal study:Changes in children ’ s behavior in the kindergarten and at home were recorded by using a self-made obser-vation sheet in order to know their adaption situation .All participants were followed up 5 weeks. [ Results] Inadaptation to kindergarten was found to be obvious among children who were new to the kin-dergarten and the time needed for their adaption was one month .Adaption to kindergarten in children with positive temperament was much better than those with negative temperament (P<0.05). [Conclusion] The temperament type of children is correlated to their kindergarten adaption .

Analysis of prognostic factors in microsurgery of intratemporal facial nerve schwannoma / 中华耳鼻咽喉头颈外科杂志

<p><b>OBJECTIVE</b>To discuss prognostic factors in microsurgery of intratemporal facial nerve schwannoma.</p><p><b>METHODS</b>Clinical and follow-up materials from 13 cases of facial nerve schwannoma were analyzed retrospectively. Spearman rank-order correlation and nonparametric Mann-Whitney U test from SPSS 10.0 for Windows was used for the analysis.</p><p><b>RESULTS</b>Each of 13 cases was operated on using modern microsurgery. Eleven cases among them received facial nerve reconstruction. One of the 13 cases lost follow-up. Others had no residue or recurrence. The House-Brackmann grades of the cases received facial nerve reconstruction were II through V. Spearman rank-order correlation showed the postoperative facial nerve function was correlated with the preoperative duration of facial nerve paralysis (r = 0.925, P = 0.000) and the preoperative facial nerve function(r = 0.712, P = 0.021). Mann-Whitney U test showed that the tumor position had no effect on the postoperative facial nerve function (P = 0.889).</p><p><b>CONCLUSIONS</b>Among most of the patients who received microsurgery of facial nerve schwannoma, facial nerve functions could be restored to great extent. The longer the preoperative duration of facial nerve paralysis or the worse the preoperative facial nerve function, the worse the postoperative facial nerve function in cases who received facial nerve resection and reconstruction. Facial nerve reconstruction was helpful for the patient with facial nerve schwannoma whose facial muscles were denervated but have fibrillation potentials, as well as for the patient whose facial nerve schwannoma intruded internal acoustic canal.</p>

Significance of galectin-3 and CD44v6 expression in differential diagnosis of thyroid nodules / 中华肿瘤杂志

<p><b>OBJECTIVE</b>To investigate the difference of galectin-3 and CD44v6 expression between benign and malignant thyroid nodules, and to evaluate their clinical value in distinguishing thyroid cancer from benign thyroid nodules.</p><p><b>METHODS</b>The expression of galectin-3 and CD44v6 was immunohistochemically detected by the ABC method in 143 benign and malignant thyroid nodule samples.</p><p><b>RESULTS</b>Expression of these two markers in benign thyroid nodules: galectin-3 was negative in 10 cases of para-cancer normal tissue and 14 cases of benign nodules found in the other benign thyroid disease. It was weakly positive in 4 of 52 nodular goiter (7.7%). Also it was weakly positive in 2 of 22 follicular adenomas (9.1%). But all three eosinophilic follicular adenomas were diffusely or focally positive for galectin-3. CD44v6 was negative in 10 cases of para-cancer normal tissue, but positive in 4 of 14 nodular lesions found in benign thyroid diseases (28.6%). It was also positive in 16 of 52 nodular goiters (30.8%), and weakly positive in 7 of 22 follicular adenomas (31.8%). The two markers in malignant lesions: galectin-3 was positive in 50 of 52 thyroid adenocarcinoma (96.2%), CD44v6 was positive in 42 of 52 thyroid adenocarcinoma (80.8%). The positive rate of galectin-3 and CD44v6 expression in thyroid cancer was significantly higher than that in benign thyroid nodule and normal tissue (P < 0.001). The sensitivity, specificity and accuracy of galectin-3 combined with CD44v6 in differentiating benign from malignant thyroid nodule were 80.8%, 93.4%, 88.8%; they were 96.2%, 90.1%, 92.3% for Galectin-3 alone.</p><p><b>CONCLUSION</b>The immunohistochemical expression of galectin-3 and CD44v6 by the ABC method is significantly higher in thyroid cancers than in benign thyroid nodules, especially galectin-3 in thyrocyte being helpful in differentiating benign thyroid nodule from thyroid cancer.</p>